As enterprises accelerate the adoption of agentic AI and cloud-native architectures, Palo Alto Networks and Google Cloud have announced a major expansion of their long-standing strategic partnership, aimed at embedding security across the full lifecycle of AI development and deployment. The collaboration seeks to address a growing trust deficit in enterprise AI by combining Google Cloud’s advanced AI infrastructure with Palo Alto Networks’ Prisma AIRS platform, creating a security-first foundation for next-generation digital businesses.
The announcement comes against a backdrop of escalating AI-related cyber risks. Palo Alto Networks’ State of Cloud Report, released in December 2025, highlights a stark reality: nearly all surveyed organisations reported at least one attempted or successful attack on their AI infrastructure over the past year. At the same time, enterprises are rapidly scaling cloud environments to support AI-driven workloads, often faster than their security frameworks can adapt.
The expanded partnership is designed to close this gap by integrating security directly into hybrid and multi cloud environments, application development pipelines, and AI runtime operations. Rather than treating security as an overlay, the joint approach positions it as a built-in layer across code, cloud and endpoints, enabling organisations to innovate with AI while safeguarding sensitive data and intellectual property.
A core pillar of the collaboration is end-to-end AI security. Enterprises running AI workloads on Google Cloud, including services such as Vertex AI and Agent Engine, will be able to deploy Prisma AIRS to protect models, data pipelines and live AI operations. The integration extends upstream to developer environments as well, securing tools such as Google Cloud’s Agent Development Kit to reduce risk at the earliest stages of AI application design. Capabilities span AI posture management, real-time runtime defence, autonomous agent protection, proactive red teaming and model vulnerability scanning.
The partnership also strengthens cloud perimeter and access security. Palo Alto Networks’ VM-Series software firewalls will now integrate more deeply with Google Cloud environments, enabling consistent threat prevention and policy enforcement across public, private and hybrid cloud deployments. In parallel, Prisma SASE will leverage Google’s global network to enhance secure access for distributed workforces, branch locations and mobile users, while maintaining uniform security controls across multi cloud architectures.
Another key focus area is operational simplicity. By pre-integrating and jointly engineering their solutions, the two companies aim to reduce deployment complexity and integration friction for enterprise security teams. This unified approach is intended to accelerate time-to-protection, streamline compliance efforts and provide consolidated visibility across increasingly complex cloud and AI environments.
Commenting on the development, Simon Green, President for Asia Pacific and Japan at Palo Alto Networks, noted that secure AI scalability has become a defining competitive factor for enterprises. He emphasised that native integration of Prisma AIRS with Google Cloud infrastructure allows organisations to deploy autonomous AI systems with confidence, ensuring that security evolves in step with innovation rather than lagging it.
Google Cloud echoed this view, with President and Chief Revenue Officer Matt Renner highlighting growing enterprise demand for seamlessly integrated security across applications and data. He said the expanded partnership ensures joint customers can protect critical AI infrastructure while building new AI agents with security embedded from the outset.
The announcement also reflects a deeper commercial and engineering alignment between the two companies. Palo Alto Networks will continue expanding its use of Google Cloud’s AI infrastructure, migrating key internal workloads under a multibillion-dollar agreement. It is also adopting Google Cloud’s Vertex AI platform and Gemini large language models to power its own AI-driven security copilots. With more than 75 existing joint integrations and over $2 billion in cumulative sales through the Google Cloud Marketplace, the partnership is evolving from interoperability to co-innovation.
As enterprises navigate a future defined by autonomous AI, cloud scale and heightened cyber risk, the Palo Alto Networks–Google Cloud alliance signals a shift toward security architectures designed not just to protect today’s systems, but to enable responsible AI growth at enterprise scale.
